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Collagen glycosylation is also possibly involved in
2020-07-31
Collagen glycosylation is also possibly involved in the etiology of auto-immune diseases. Glycosylation plays a role in the recognition of collagen peptides by the adaptive immune system. In mice, immunization with heterologous collagen type II yields T-cells restricted to an immuno-dominant glycope
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There is no evidence for Complex I presence
2020-07-30
There is no evidence for Complex I presence in the P. falciparum mitochondrial 2750 transport chain, but bioinformatic analysis has identified the type II NADH dehydrogenase (PfNDH2) (Gardner et al. 2002). Analysis of the PfNDH2 gene indicates that the PfNDH2 protein is a single 52kDa monomer and p
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The binding of collagen X
2020-07-30
The binding of collagen X to DDR2 differs from the binding of collagen X to α2β1 integrin in that the triple helical conformation is essential for DDR2 binding. We previously reported that heat denatured pepsinised collagen X supported cell adhesion via α2β1, indicating that the triple-helical confo
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Altogether we have shown the presence of fully methylated DA
2020-07-30
Altogether we have shown the presence of fully methylated DAPK fragments in serum of ovarian cancer patients but also of women with uterine leiomyoma. This indicates the prerequisite for the analysis of not only healthy controls but also of women with other frequent non-cancer disease for the valida
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The in vitro studies support our previous observations of a
2020-07-30
The in vitro studies support our previous observations of a bimodal expression pattern of B. malayi transcripts after tetracycline treatment, including the two enzymes we studied here. We hypothesize that this bimodal expression may be due to stage-specific responses of the host in response to Wolba
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An integral feature of cereal seed growth development and ge
2020-07-30
An integral feature of cereal seed growth (development and germination) is the programed cell death of its individual tissues. Maternal tissues, such as the nucellus and pericarp, undergo progressive degeneration via PCD during the early stages of seed development. This process allows mobilization o
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Activation of CDK involves binding of CDKs with their
2020-07-30
Activation of CDK involves binding of CDKs with their respective cyclins at the C-terminal via noncovalent interactions and leads to the accessibility of ATP to the catalytic site for phosphorylation of threonine. A list depicting the association of cyclins with CDKs and their overexpression in var
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Chemokine receptors are a large
2020-07-30
Chemokine receptors are a large superfamily of G protein-coupled receptors containing 7 transmembrane domains that are predominantly localized on the surface of leukocytes (Kakinuma and Hwang, 2006). These receptors contain a short acidic N-terminal end, seven helical transmembrane domains with thre
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Acute renal failure in cats can arise from
2020-07-30
Acute renal failure in cats can arise from numerous causes [34], [35], [36], [37], [38], [39], [40] and has a very poor prognosis [36], [41]. Many cats who survive to discharge are azotaemic and, as a result, are likely to have high morbidity and greatly-reduced lifespan, while a second “wave” of ap
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To evaluate the new quadrupolar CPA qCPA the pure fluid
2020-07-30
To evaluate the new quadrupolar CPA (qCPA) the pure fluid properties of CO2 are predicted both in the critical region and in the compressed liquid region. The model is furthermore applied for the prediction and correlation of binary mixtures with CO2 and n-alkanes, water, alcohols and a few quadrupo
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br Results and discussion As explained
2020-07-30
Results and discussion As explained in detail in the Theory section, one of the highly recommended approaches in thermodynamics to model vapor-liquid equilibria at low pressure conditions is the γ−ϕ approach. Following this approach, in order to have greatly reliable results for the challenging s
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br Conflict of interest br Acknowledgments Part of this
2020-07-30
Conflict of interest Acknowledgments Part of this work was supported by Institut Francais en Egypte, and the Academy of Scientific Research and Technology in Egypt under the frame of “Imhotep Project N°: 31681XL” and “STDF/IFE project N° 30630″ Introduction NSAIDs play an important role in
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An interesting feature of most if not all the Pro
2020-07-30
An interesting feature of most, if not all the Pro residues in the Yaa position of mammalian collagens is that they are modified to 4-hydroxyproline (Hyp) residues. This occurs during intracellular biosynthesis, prior to the three individual chains folding to give a triple helical structure [3]. Thi
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azd9291 The presence of segmental duplications in the
2020-07-30
The presence of segmental duplications in the genome of A. thaliana indicate that it has a polyploid origin [5], [6], [7]. It has been proposed that this species might have originated from an ancestral genome of n=4 azd9291 undergoing polyploidization resulting in species of n=8 chromosomes. This a
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Significantly elevated levels of DNA damage observed
2020-07-30
Significantly elevated levels of DNA damage observed in peripheral blood of tea garden women workers indicate the occupational exposure. The same was observed in cholinesterase activities, which detected lower activity in the exposed group compared to non-exposed. Large volumes of pesticides are use
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