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Reviewing the literature we knew that
2019-06-14
Reviewing the literature, we knew that in cases of AA, use of IST should be cautious, as IST might accelerate occult lymphoma escaping immune surveillance and evolving as a refractory lymphoma. Second, in cases of AA and concomitant NHL, to choose cytotoxic chemotherapy or IST is an art. Depending o
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br Discussion T wave oversensing is
2019-06-14
Discussion T-wave oversensing is caused by alternations or variations in intracardiac electrograms for reasons such as hyperglycemia, drugs, sympathetic tones, ventricular pacing, and hyperkalemia. Several similar cases of hyperkalemia-induced T-wave oversensing with inappropriate ICD therapies h
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This week delegates are gathered in Abu Dhabi United
2019-06-14
This week, delegates are gathered in Abu Dhabi, United Arab Emirates, for the . A large portion of the programme will be dedicated to global progress on demand reduction measures laid out in WHO\'s (FCTC), which celebrated its 10th birthday last month. Adopted at the 56th World Health Assembly in 2
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Whole body CT only showed mild
2019-06-14
Whole-body CT only showed mild splenomegaly (14cm) and an enlarged iliac lymph node (1.5×3cm). Cranial MR yielded no specific findings. In the meantime, the patient was given Rituximab. He received 375mg/m2 of Rituximab per week, but after the third dose the patient rapidly developed shock and abdo
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Upper gastrointestinal bleeding secondary to peptic ulcer di
2019-06-14
Upper gastrointestinal bleeding secondary to peptic ulcer disease is a common life-threatening medical condition. However, historically, peptic ulcer disease was an uncommon ailment. The rise in the incidence of peptic ulcer disease occurred in the mid-1800s. At that time, studies in North America a
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Premature deaths of women have
2019-06-13
Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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After overdrive pacing excitation that is one lap
2019-06-13
After overdrive pacing, excitation that is one lap behind (the second beat after the stimulus) is caused by several mechanisms. One is the prolonged conduction time that is longer than the TCL due to a long conduction pathway and/or slow conduction. The other is the dual-loop reentry [12]. The excit
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Any abnormality causing a loss of function in the IKs
2019-06-13
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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br Materials and methods br Results br Discussion br Conclus
2019-06-13
Materials and methods Results Discussion Conclusions Immediate ablation discontinuation during pulmonary vein isolation remarkably decreased the incidence of EsoTLs, even when using STS. EsoTL did occur after AFRA with immediate ablation discontinuation at the esophageal temperature prob
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It must be noted that modern physical techniques for
2019-06-13
It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop
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br The slow progress in endemicity mapping of
2019-06-13
The slow progress in endemicity mapping of neglected tropical diseases (NTDs) in Africa and scaling up of mass drug administration (MDA) in all endemic countries has hampered efforts to meet the London 2020 elimination and control targets. Lymphatic filariasis is targeted to be eliminated by 2020;
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br Case report A year old man
2019-06-12
Case report A 67-year-old man with a past history of hepatitis B carrier presented with body weight loss of 10 kg, general weakness and abdominal fullness for three months and was admitted for the impression of decompensated liver cirrhosis. Physical examination of the patient revealed a diffuse
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The combination therapy was exceedingly well tolerated witho
2019-06-12
The combination therapy was exceedingly well tolerated without any side effects to either drug. Remarkably, despite an advanced PV-stage the JAK2V617F allele burden was rapidly lowered from 90% mutated kainic acid at referral to 59% at 6 months, 28% at 10 months and 12% at 16 months of therapy (Fig
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Of note cases reported by Britton et al and Keung
2019-06-12
Of note, cases reported by Britton et al. and Keung et al. rely on the demonstration of CD7 and TDT along with myeloid markers to classify the blasts as “biphenotypic” [8,9]. Expression of CD3 is not reported by the authors and these cases would not meet the current 2008 WHO criteria for MPAL. Age
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br Possible reasons for the divergent
2019-06-12
Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site
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