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Although the ferromagnetic particles and T
2020-08-06
Although the ferromagnetic particles and T4 RO4987655 receptor on the particles were heated by the ac magnetic field, the average temperature of the reaction solution as a whole was kept suitably low for the annealing of DNA ends (16°C). Indeed, no appreciable increase in the temperature of the reac
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The DDR gene is located in q and
2020-08-06
The DDR2 gene is located in 1q23.3, and its product is a tyrosine kinase receptor for fibrillar collagen [7], [8], [9], [10]. Under normal physiological conditions, it acts in cutaneous wound healing mediated by proliferation, chemotactic migration, and secretion of metalloproteinases and collagen b
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The enantiomeric ratio ER of
2020-08-06
The enantiomeric ratio (ER) of chiral compounds accumulated in organisms has been found to be different among species (Borga and Bidleman, 2005, Harner et al., 1999, Warner et al., 2005, Wiberg et al., 2000), indicating enantioselective accumulation of chiral compounds are species-specific. The ER o
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Crm regulates these factors by interacting with their
2020-08-06
Crm1 regulates these factors by interacting with their NES and targeting them spatially and temporally to centrosomes. It is likely that Crm1 supplies a docking site for these factors at centrosomes and regulates their localization and function . But it is still unknown the mechanism for Crm1 to tar
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Other GPCRs notable for changes in expression on CLL cells
2020-08-05
Other GPCRs notable for changes in expression on CLL cells include upregulation of the thromboxane A2 receptor TBXA2R mRNA [61] and up and downregulation of mRNA and protein from the neurotensin receptors NTSR2 and NTSR1, respectively [62]. The Eμ-TCL1 mouse model of CLL has been used to study mult
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br Conclusions br Conflict of interest br
2020-08-05
Conclusions Conflict of interest Acknowledgments This research was supported by International Society of Hypertension (ISH) grant for mentors (2017) and Association of African Universities (AAU; 2017). Introduction Standard treatment for hypoglycemia is administration of dextrose but it
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Recent studies have reported the co localization
2020-08-05
Recent studies have reported the co-localization of total and pDDRs in Sodium Aescinate with collagen [20], [21], [35]. Our results expand these observations by showing that higher-order assembly of DDRs into receptor clusters and/or filamentous structures may associate with different morphological
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According to Graeff Graeff innate fear is mediated
2020-08-05
According to Graeff (Graeff, 1990), innate fear is mediated by neural circuitry that consists of at least the amygdala, medial hypothalamus and periaqueductal grey matter. In particular, the BLA has been considered to be a structure closely related to emotional responses to fear, stress and anxiety
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Clinical studies have shown that the degree of metabolic alt
2020-08-05
Clinical studies have shown that the degree of metabolic alteration varied by type and dose of the progestogen component [13] and that the higher androgenic formulations consistently had the strongest effects [14], [15]. Although, our finding that high dose progestogen-containing combined OC produce
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To gather more insights into the catalytic mechanism
2020-08-05
To gather more insights into the catalytic mechanism of RHA-Phis for a future fine-tuning of this biotechnologically relevant enzyme, a combined approach of sequence alignment and homology modeling was used. The alignment of RHA-P sequence with 130 homologs of the GH106 family allowed identifying fi
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br Data availability br Acknowledgments The work was
2020-08-04
Data availability Acknowledgments The work was supported in Department of Biochemistry by grants from British Heart Foundation (SP/15/7/31561, FS/15/20/31335 and RG/15/4/31268). At the Department of Materials Science, Cambridge, funding was from the People Programme of the EU 7th Framework Pro
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The first step in the biosynthesis of
2020-08-04
The first step in the biosynthesis of steroid hormones is the translocation of cholesterol into the inner mitochondrial membrane, a process regulated by the steroidogenic acute regulatory protein STARD1 (also known as StAR), which is believed to act as a shuttle enzyme (Miller & Strauss, 1999). This
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The production of papaya and pineapple around the
2020-08-04
The production of papaya and pineapple around the world, is characterized by generating a volume of waste close to 25% for papaya (seeds and peels) and 50% for pineapple (Ketnawa et al., 2012, Ordoñez et al., 2016), not counting the harvest surpluses and the rejected fruits (green and ripe). In Colo
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The rate of protein degradation
2020-08-04
The rate of protein degradation is often affected by N-starvation [12], therefore, we examined the influence of N-starvation against the appearance of CEPs. N-starved cucumber cotyledons contained less amounts of protein and Rubisco, but the temporal changes in protein and Rubisco contents were sim
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Introduction Collagen fibrillogenesis the assembly of collag
2020-08-04
Introduction Collagen fibrillogenesis, the assembly of collagen fibers, is a critical process in the development, maturation, and repair of mammalian tissue. Alterations in the structure and amount of deposited collagen fibers can greatly alter the integrity of the whole tissue. Even a single point
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